Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia

Leukemia stem cells (LSC) possess distinct self-renewal and arrested differentiation properties that are responsible for disease emergence, therapy failure, and recurrence in acute myeloid leukemia (AML). Despite AML displaying extensive biological and clinical heterogeneity, LSC with high interleuk...

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Detalles Bibliográficos
Autores principales: Kan, Winnie L., Dhagat, Urmi, Kaufmann, Kerstin B., Hercus, Timothy R., Nero, Tracy L., Zeng, Andy G.X., Toubia, John, Barry, Emma F., Broughton, Sophie E., Gomez, Guillermo A., Benard, Brooks A., Dottore, Mara, Cheung Tung Shing, Karen S., Boutzen, Héléna, Samaraweera, Saumya E., Simpson, Kaylene J., Jin, Liqing, Goodall, Gregory J., Begley, C. Glenn, Thomas, Daniel, Ekert, Paul G., Tvorogov, Denis, D'Andrea, Richard J., Dick, John E., Parker, Michael W., Lopez, Angel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401075/
https://www.ncbi.nlm.nih.gov/pubmed/37191437
http://dx.doi.org/10.1158/2159-8290.CD-22-1396

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