Deep brain stimulation suppresses epileptic seizures in rats via inhibition of adenosine kinase and activation of adenosine A1 receptors

AIMS: Deep brain stimulation (DBS) of the anterior nucleus of the thalamus, is an effective therapy for patients with drug‐resistant epilepsy, yet, its mechanism of action remains elusive. Adenosine kinase (ADK), a key negative regulator of adenosine, is a potential modulator of epileptogenesis. DBS...

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Detalles Bibliográficos
Autores principales: Xie, Pandeng, Liu, Siqi, Huang, Qi, Xiong, Zhonghua, Deng, Jiahui, Tang, Chongyang, Xu, Ke, Zhang, Bo, He, Baijian, Wang, Xiongfei, Liu, Zhao, Wang, Jing, Zhou, Jian, Guan, Yugang, Luan, Guoming, Li, Tianfu, Zhai, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401158/
https://www.ncbi.nlm.nih.gov/pubmed/37017409
http://dx.doi.org/10.1111/cns.14199

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