Cargando…
Sandwich‐Structured Implants to Obstruct Multipath Energy Supply and Trigger Self‐Enhanced Hypoxia‐Initiated Chemotherapy Against Postsurgical Tumor Recurrence and Metastasis (Adv. Sci. 22/2023)
Postsurgical Tumor Therapy with In Situ Implantation In article number 2300899, Yanteng Xu, Zhaohui Tang, Yu Tao, Mingqiang Li, and co‐workers report an implantable sandwich‐structured dual‐drug depot to achieve self‐enhanced postsurgical tumor treatment through starvation therapy and hypoxia‐induce...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401163/ http://dx.doi.org/10.1002/advs.202370150 |
_version_ | 1785084596267778048 |
---|---|
author | Fang, Youqiang Luo, Xing Xu, Yanteng Liu, Zheng Mintz, Rachel L. Yu, Haiyang Yu, Xuan Li, Kai Ju, Enguo Wang, Haixia Tang, Zhaohui Tao, Yu Li, Mingqiang |
author_facet | Fang, Youqiang Luo, Xing Xu, Yanteng Liu, Zheng Mintz, Rachel L. Yu, Haiyang Yu, Xuan Li, Kai Ju, Enguo Wang, Haixia Tang, Zhaohui Tao, Yu Li, Mingqiang |
author_sort | Fang, Youqiang |
collection | PubMed |
description | Postsurgical Tumor Therapy with In Situ Implantation In article number 2300899, Yanteng Xu, Zhaohui Tang, Yu Tao, Mingqiang Li, and co‐workers report an implantable sandwich‐structured dual‐drug depot to achieve self‐enhanced postsurgical tumor treatment through starvation therapy and hypoxia‐induced chemotherapy that are triggered in sequence. The postsurgical adjuvant treatment with combretastatin A4 phosphate and tirapazamineloaded implants efficiently inhibits tumor recurrence and metastasis, showing great potential for clinical applications. [Image: see text] |
format | Online Article Text |
id | pubmed-10401163 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104011632023-08-05 Sandwich‐Structured Implants to Obstruct Multipath Energy Supply and Trigger Self‐Enhanced Hypoxia‐Initiated Chemotherapy Against Postsurgical Tumor Recurrence and Metastasis (Adv. Sci. 22/2023) Fang, Youqiang Luo, Xing Xu, Yanteng Liu, Zheng Mintz, Rachel L. Yu, Haiyang Yu, Xuan Li, Kai Ju, Enguo Wang, Haixia Tang, Zhaohui Tao, Yu Li, Mingqiang Adv Sci (Weinh) Back Cover Postsurgical Tumor Therapy with In Situ Implantation In article number 2300899, Yanteng Xu, Zhaohui Tang, Yu Tao, Mingqiang Li, and co‐workers report an implantable sandwich‐structured dual‐drug depot to achieve self‐enhanced postsurgical tumor treatment through starvation therapy and hypoxia‐induced chemotherapy that are triggered in sequence. The postsurgical adjuvant treatment with combretastatin A4 phosphate and tirapazamineloaded implants efficiently inhibits tumor recurrence and metastasis, showing great potential for clinical applications. [Image: see text] John Wiley and Sons Inc. 2023-08-04 /pmc/articles/PMC10401163/ http://dx.doi.org/10.1002/advs.202370150 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Back Cover Fang, Youqiang Luo, Xing Xu, Yanteng Liu, Zheng Mintz, Rachel L. Yu, Haiyang Yu, Xuan Li, Kai Ju, Enguo Wang, Haixia Tang, Zhaohui Tao, Yu Li, Mingqiang Sandwich‐Structured Implants to Obstruct Multipath Energy Supply and Trigger Self‐Enhanced Hypoxia‐Initiated Chemotherapy Against Postsurgical Tumor Recurrence and Metastasis (Adv. Sci. 22/2023) |
title | Sandwich‐Structured Implants to Obstruct Multipath Energy Supply and Trigger Self‐Enhanced Hypoxia‐Initiated Chemotherapy Against Postsurgical Tumor Recurrence and Metastasis (Adv. Sci. 22/2023) |
title_full | Sandwich‐Structured Implants to Obstruct Multipath Energy Supply and Trigger Self‐Enhanced Hypoxia‐Initiated Chemotherapy Against Postsurgical Tumor Recurrence and Metastasis (Adv. Sci. 22/2023) |
title_fullStr | Sandwich‐Structured Implants to Obstruct Multipath Energy Supply and Trigger Self‐Enhanced Hypoxia‐Initiated Chemotherapy Against Postsurgical Tumor Recurrence and Metastasis (Adv. Sci. 22/2023) |
title_full_unstemmed | Sandwich‐Structured Implants to Obstruct Multipath Energy Supply and Trigger Self‐Enhanced Hypoxia‐Initiated Chemotherapy Against Postsurgical Tumor Recurrence and Metastasis (Adv. Sci. 22/2023) |
title_short | Sandwich‐Structured Implants to Obstruct Multipath Energy Supply and Trigger Self‐Enhanced Hypoxia‐Initiated Chemotherapy Against Postsurgical Tumor Recurrence and Metastasis (Adv. Sci. 22/2023) |
title_sort | sandwich‐structured implants to obstruct multipath energy supply and trigger self‐enhanced hypoxia‐initiated chemotherapy against postsurgical tumor recurrence and metastasis (adv. sci. 22/2023) |
topic | Back Cover |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401163/ http://dx.doi.org/10.1002/advs.202370150 |
work_keys_str_mv | AT fangyouqiang sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT luoxing sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT xuyanteng sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT liuzheng sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT mintzrachell sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT yuhaiyang sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT yuxuan sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT likai sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT juenguo sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT wanghaixia sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT tangzhaohui sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT taoyu sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 AT limingqiang sandwichstructuredimplantstoobstructmultipathenergysupplyandtriggerselfenhancedhypoxiainitiatedchemotherapyagainstpostsurgicaltumorrecurrenceandmetastasisadvsci222023 |