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A new aerodynamic endonasal filtration technology for protection against pollutants and respiratory infectious agents: evaluation of the particle filtration efficacy

An innovative nasal filter was tested, based on aerodynamic air filtration and not on conventional air filtration by means of mesh filters. A custom testing system was designed and three sizes of the filter have been tested vs. monodispersed SiO(2) particles sized 5 μm, 1 μm, and 0.5 μm under cyclin...

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Autores principales: Saravanan, Padmanabhan, Broccolo, Francesco, Ali, Nurshahidah, Toh, Alden, Mulyana, Sakinah, Beng, Goh Lay, Imperi, Enrico, Picano, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401429/
https://www.ncbi.nlm.nih.gov/pubmed/37546386
http://dx.doi.org/10.3389/fmedt.2023.1219996
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author Saravanan, Padmanabhan
Broccolo, Francesco
Ali, Nurshahidah
Toh, Alden
Mulyana, Sakinah
Beng, Goh Lay
Imperi, Enrico
Picano, Alfredo
author_facet Saravanan, Padmanabhan
Broccolo, Francesco
Ali, Nurshahidah
Toh, Alden
Mulyana, Sakinah
Beng, Goh Lay
Imperi, Enrico
Picano, Alfredo
author_sort Saravanan, Padmanabhan
collection PubMed
description An innovative nasal filter was tested, based on aerodynamic air filtration and not on conventional air filtration by means of mesh filters. A custom testing system was designed and three sizes of the filter have been tested vs. monodispersed SiO(2) particles sized 5 μm, 1 μm, and 0.5 μm under cycling flow of 6 liters per minute, provided by an artificial lung breather simulating spontaneous breathing. Accelerated testing was implemented, challenging filters with a maximum load of 200 mg per cubic meter. All three filters' sizes showed initial filtration efficiencies above 90% vs. all particles' sizes, decreased to not less than 80% after 30 min of accelerated testing, corresponding to 4.5 days of continuous use at 2 mg challenge, this value being associated with hazardous air conditions in the PSI scale. Results in this study indicate that nasal filters based on aerodynamic air filtration can provide fine and ultrafine filtration, offering protection in day-to-day life from risks associated with pollens, mites, PM, pollutants, and respiratory infectious agents, introducing acceptable respiratory resistance.
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spelling pubmed-104014292023-08-05 A new aerodynamic endonasal filtration technology for protection against pollutants and respiratory infectious agents: evaluation of the particle filtration efficacy Saravanan, Padmanabhan Broccolo, Francesco Ali, Nurshahidah Toh, Alden Mulyana, Sakinah Beng, Goh Lay Imperi, Enrico Picano, Alfredo Front Med Technol Medical Technology An innovative nasal filter was tested, based on aerodynamic air filtration and not on conventional air filtration by means of mesh filters. A custom testing system was designed and three sizes of the filter have been tested vs. monodispersed SiO(2) particles sized 5 μm, 1 μm, and 0.5 μm under cycling flow of 6 liters per minute, provided by an artificial lung breather simulating spontaneous breathing. Accelerated testing was implemented, challenging filters with a maximum load of 200 mg per cubic meter. All three filters' sizes showed initial filtration efficiencies above 90% vs. all particles' sizes, decreased to not less than 80% after 30 min of accelerated testing, corresponding to 4.5 days of continuous use at 2 mg challenge, this value being associated with hazardous air conditions in the PSI scale. Results in this study indicate that nasal filters based on aerodynamic air filtration can provide fine and ultrafine filtration, offering protection in day-to-day life from risks associated with pollens, mites, PM, pollutants, and respiratory infectious agents, introducing acceptable respiratory resistance. Frontiers Media S.A. 2023-07-21 /pmc/articles/PMC10401429/ /pubmed/37546386 http://dx.doi.org/10.3389/fmedt.2023.1219996 Text en © 2023 Saravanan, Broccolo, Ali, Toh, Mulyana, Beng, Imperi and Picano. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medical Technology
Saravanan, Padmanabhan
Broccolo, Francesco
Ali, Nurshahidah
Toh, Alden
Mulyana, Sakinah
Beng, Goh Lay
Imperi, Enrico
Picano, Alfredo
A new aerodynamic endonasal filtration technology for protection against pollutants and respiratory infectious agents: evaluation of the particle filtration efficacy
title A new aerodynamic endonasal filtration technology for protection against pollutants and respiratory infectious agents: evaluation of the particle filtration efficacy
title_full A new aerodynamic endonasal filtration technology for protection against pollutants and respiratory infectious agents: evaluation of the particle filtration efficacy
title_fullStr A new aerodynamic endonasal filtration technology for protection against pollutants and respiratory infectious agents: evaluation of the particle filtration efficacy
title_full_unstemmed A new aerodynamic endonasal filtration technology for protection against pollutants and respiratory infectious agents: evaluation of the particle filtration efficacy
title_short A new aerodynamic endonasal filtration technology for protection against pollutants and respiratory infectious agents: evaluation of the particle filtration efficacy
title_sort new aerodynamic endonasal filtration technology for protection against pollutants and respiratory infectious agents: evaluation of the particle filtration efficacy
topic Medical Technology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401429/
https://www.ncbi.nlm.nih.gov/pubmed/37546386
http://dx.doi.org/10.3389/fmedt.2023.1219996
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