Analysis of structure–activity and structure–mechanism relationships among thyroid stimulating hormone receptor binding chemicals by leveraging the ToxCast library

The thyroid stimulating hormone receptor (TSHR) is crucial in thyroid hormone production in humans, and dysregulation in TSHR activation can lead to adverse health effects such as hypothyroidism and Graves' disease. Further, animal studies have shown that binding of endocrine disrupting chemica...

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Detalles Bibliográficos
Autores principales: Sahoo, Ajaya Kumar, Baskaran, Shanmuga Priya, Chivukula, Nikhil, Kumar, Kishan, Samal, Areejit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401517/
https://www.ncbi.nlm.nih.gov/pubmed/37546222
http://dx.doi.org/10.1039/d3ra04452a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401517/
https://www.ncbi.nlm.nih.gov/pubmed/37546222
http://dx.doi.org/10.1039/d3ra04452a

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