Cargando…

Ligand-independent activation of platelet-derived growth factor receptor β promotes vitreous-induced contraction of retinal pigment epithelial cells

BACKGROUND: Epiretinal membranes in patients with proliferative vitreoretinopathy (PVR) consist of extracellular matrix and a number of cell types including retinal pigment epithelial (RPE) cells and fibroblasts, whose contraction causes retinal detachment. In RPE cells depletion of platelet-derived...

Descripción completa

Detalles Bibliográficos
Autores principales: Duan, Yajian, Wu, Wenyi, Cui, Jing, Matsubara, Joanne Aiko, Kazlauskas, Andrius, Ma, Gaoen, Li, Xiaorong, Lei, Hetian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401781/
https://www.ncbi.nlm.nih.gov/pubmed/37537538
http://dx.doi.org/10.1186/s12886-023-03089-8