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Ligand-independent activation of platelet-derived growth factor receptor β promotes vitreous-induced contraction of retinal pigment epithelial cells
BACKGROUND: Epiretinal membranes in patients with proliferative vitreoretinopathy (PVR) consist of extracellular matrix and a number of cell types including retinal pigment epithelial (RPE) cells and fibroblasts, whose contraction causes retinal detachment. In RPE cells depletion of platelet-derived...
Autores principales: | Duan, Yajian, Wu, Wenyi, Cui, Jing, Matsubara, Joanne Aiko, Kazlauskas, Andrius, Ma, Gaoen, Li, Xiaorong, Lei, Hetian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401781/ https://www.ncbi.nlm.nih.gov/pubmed/37537538 http://dx.doi.org/10.1186/s12886-023-03089-8 |
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