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The importance of clinical importance when determining the target difference in sample size calculations
Recently, it was argued that clinically important differences should play no role in sample size calculations. Instead, it was proposed that sample size calculations should focus on setting realistic estimates of treatment benefit. We disagree, and argue in this article that considering the importan...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401796/ https://www.ncbi.nlm.nih.gov/pubmed/37542276 http://dx.doi.org/10.1186/s13063-023-07532-5 |