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Transgenic disruption of endogenous glucocorticoid signaling in osteoblasts does not alter long-term K/BxN serum transfer-induced arthritis

BACKGROUND: Disruption of glucocorticoid (GC) signaling in osteoblasts results in a marked attenuation of acute antibody-induced arthritis. The role of endogenous GCs in chronic inflammatory arthritis is however not fully understood. Here, we investigated the impact of endogenous GC signaling in ost...

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Detalles Bibliográficos
Autores principales: Maleitzke, Tazio, Wiebe, Edgar, Huscher, Dörte, Spies, Cornelia M., Tu, Jinwen, Gaber, Timo, Zheng, Yu, Buttgereit, Frank, Seibel, Markus J., Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401869/
https://www.ncbi.nlm.nih.gov/pubmed/37542341
http://dx.doi.org/10.1186/s13075-023-03112-9