Cargando…

Transgenic disruption of endogenous glucocorticoid signaling in osteoblasts does not alter long-term K/BxN serum transfer-induced arthritis

BACKGROUND: Disruption of glucocorticoid (GC) signaling in osteoblasts results in a marked attenuation of acute antibody-induced arthritis. The role of endogenous GCs in chronic inflammatory arthritis is however not fully understood. Here, we investigated the impact of endogenous GC signaling in ost...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maleitzke, Tazio, Wiebe, Edgar, Huscher, Dörte, Spies, Cornelia M., Tu, Jinwen, Gaber, Timo, Zheng, Yu, Buttgereit, Frank, Seibel, Markus J., Zhou, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401869/ https://www.ncbi.nlm.nih.gov/pubmed/37542341 http://dx.doi.org/10.1186/s13075-023-03112-9

Ejemplares similares

Acute murine antigen-induced arthritis is not affected by disruption of osteoblastic glucocorticoid signalling
por: Spies, Cornelia M, et al.
Publicado: (2014)

Arthritogenic Monoclonal Antibodies from K/BxN Mice
por: Maccioni, Mariana, et al.
Publicado: (2002)

Temporomandibular joint damage in K/BxN arthritic mice
por: Kuchler-Bopp, Sabine, et al.
Publicado: (2020)

The neuropathic phenotype of the K/BxN transgenic mouse with spontaneous arthritis: pain, nerve sprouting and joint remodeling
por: Gonçalves dos Santos, Gilson, et al.
Publicado: (2020)

Akkermansia muciniphila is permissive to arthritis in the K/BxN mouse model of arthritis
por: Stoll, Matthew L, et al.
Publicado: (2018)

Heme Oxygenase-1 Regulates the Progression of K/BxN Serum Transfer Arthritis
por: Brines, Rita, et al.
Publicado: (2012)

K/BxN Serum-Transfer Arthritis as a Model for Human Inflammatory Arthritis
por: Christensen, Anne D., et al.
Publicado: (2016)

PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis
por: Rohrbach, Amanda S, et al.
Publicado: (2012)

Induction of Krüppel‐like factor 2 reduces K/BxN serum‐induced arthritis
por: Das, Manjusri, et al.
Publicado: (2018)

Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis
por: Almizraq, Ruqayyah J., et al.
Publicado: (2023)

A critical role for leukotriene B(4 )in K/BxN serum transfer arthritis pathogenesis
por: Chen, M, et al.
Publicado: (2004)

Mast cells jump start K/BxN serum transfer arthritis via IL-1
por: Nigrovic, PA, et al.
Publicado: (2007)

Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency
por: Martin, Praxedis, et al.
Publicado: (2013)

Myeloid Krüppel-Like Factor 2 Critically Regulates K/BxN Serum-Induced Arthritis
por: Das, Manjusri, et al.
Publicado: (2019)

The impact of age and gut microbiota on Th17 and Tfh cells in K/BxN autoimmune arthritis
por: Teng, Fei, et al.
Publicado: (2017)

Mechanism of Immunoregulatory Properties of Vasoactive Intestinal Peptide in the K/BxN Mice Model of Autoimmune Arthritis
por: Leceta, Javier, et al.
Publicado: (2021)

Assessment of mesenchymal stem/stromal cell-based therapy in K/BxN serum transfer-induced arthritis
por: Lopez-Santalla, Mercedes, et al.
Publicado: (2022)

The role of interleukin-18 and interleukin-18 binding protein in K/BxN serum transfer-induced arthritis
por: Fauteux-Daniel, Sebastien, et al.
Publicado: (2023)

Cartilage-protective effects of C-type natriuretic peptide over expression in K/BxN TCR arthritis model
por: Bukulmez, Hulya, et al.
Publicado: (2012)

Optimising both disease control and glucocorticoid dosing is essential for bone protection in patients with rheumatic disease
por: Wiebe, Edgar, et al.
Publicado: (2022)

Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model
por: García, Samuel, et al.
Publicado: (2010)

ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model
por: Archer, Amy M., et al.
Publicado: (2016)

Loss of Murine FOXO3 in Cells of the Myeloid Lineage Enhances Myelopoiesis but Protects from K/BxN-Serum Transfer-Induced Arthritis
por: Kang, Hannah, et al.
Publicado: (2015)

New insights into the fascinating world of glucocorticoids: the dexamethasone-miR-342-Rictor axis in regulatory T cells
por: Buttgereit, Frank, et al.
Publicado: (2021)

Circadian rhythms in rheumatology - a glucocorticoid perspective
por: Spies, Cornelia M, et al.
Publicado: (2014)

Arthritis and the role of endogenous glucocorticoids
por: Macfarlane, Eugenie, et al.
Publicado: (2020)

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System
por: Strehl, Cindy, et al.
Publicado: (2019)

Low-Dose Radiotherapy Leads to a Systemic Anti-Inflammatory Shift in the Pre-Clinical K/BxN Serum Transfer Model and Reduces Osteoarthritic Pain in Patients
por: Weissmann, Thomas, et al.
Publicado: (2022)

The supplementary therapeutic DMARD role of low-dose glucocorticoids in rheumatoid arthritis
por: Cutolo, Maurizio, et al.
Publicado: (2014)

Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer
por: Lewis, Bonnie J. B., et al.
Publicado: (2019)

The Anti-Glucocorticoid Receptor Antibody Clone 5E4: Raising Awareness of Unspecific Antibody Binding
por: Ehlers, Lisa, et al.
Publicado: (2022)

Euphorbia Factor L2 ameliorates the Progression of K/BxN Serum-Induced Arthritis by Blocking TLR7 Mediated IRAK4/IKKβ/IRF5 and NF-kB Signaling Pathways
por: Tang, Jing, et al.
Publicado: (2021)

Increased benzoxazinoid (Bx) levels in wheat seedlings via jasmonic acid treatment and etiolation and their effects on Bx genes including Bx6
por: Sue, Masayuki, et al.
Publicado: (2021)

Plant-derived pectin nanocoatings to prevent inflammatory cellular response of osteoblasts following Porphyromonas gingivalis infection
por: Meresta, Anna, et al.
Publicado: (2017)

Molecular Characterization and Functional Analysis of Three Autophagy Genes, BxATG5, BxATG9, and BxATG16, in Bursaphelenchus xylophilus
por: Liu, Hong-Bin, et al.
Publicado: (2019)

A case report of cutaneous mucormycosis of the hand after minor trauma in a patient with acute myeloid leukaemia
por: Maleitzke, Tazio, et al.
Publicado: (2019)

Nanocoating with plant-derived pectins activates osteoblast response in vitro
por: Folkert, J, et al.
Publicado: (2016)

Serum proteomics in giant cell arteritis in response to a three-day pulse of glucocorticoid followed by tocilizumab monotherapy (the GUSTO trial)
por: Christ, Lisa, et al.
Publicado: (2023)

Glucocorticoids Are Not Associated with Bone Mineral Density in Patients with Polymyalgia Rheumatica, Giant Cell Arteritis and Other Vasculitides—Cross-Sectional Baseline Analysis of the Prospective Rh-GIOP Cohort
por: Palmowski, Andriko, et al.
Publicado: (2022)

Osteoblastic glucocorticoid signaling exacerbates high-fat-diet- induced bone loss and obesity
por: Kim, Sarah, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0586fuv7hq44ak8qitb6u0rbip