Adaptive therapy achieves long-term control of chemotherapy resistance in high grade ovarian cancer

Drug resistance results in poor outcomes for most patients with metastatic cancer. Adaptive Therapy (AT) proposes to address this by exploiting presumed fitness costs incurred by drug-resistant cells when drug is absent, and prescribing dose reductions to allow fitter, sensitive cells to re-grow and...

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Detalles Bibliográficos
Autores principales: Hockings, Helen, Lakatos, Eszter, Huang, Weini, Mossner, Maximilian, Khan, Mohammed Ateeb, Metcalf, Stephen, Nicolini, Francesco, Smith, Kane, Baker, Ann-Marie, Graham, Trevor A., Lockley, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401956/
https://www.ncbi.nlm.nih.gov/pubmed/37546942
http://dx.doi.org/10.1101/2023.07.21.549688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401956/
https://www.ncbi.nlm.nih.gov/pubmed/37546942
http://dx.doi.org/10.1101/2023.07.21.549688

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