Molecular insight into how the position of an abasic site and its sequence environment influence DNA duplex stability and dynamics

Local perturbations to DNA base-pairing stability from lesions and chemical modifications can alter the stability and dynamics of an entire oligonucleotide. End effects may cause the position of a disruption within a short duplex to influence duplex stability and structural dynamics, yet this aspect...

Descripción completa

Detalles Bibliográficos
Autores principales: Ashwood, Brennan, Jones, Michael S., Lee, Yumin, Sachleben, Joseph R., Ferguson, Andrew L., Tokmakoff, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401965/
https://www.ncbi.nlm.nih.gov/pubmed/37546925
http://dx.doi.org/10.1101/2023.07.22.550182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401965/
https://www.ncbi.nlm.nih.gov/pubmed/37546925
http://dx.doi.org/10.1101/2023.07.22.550182

Ejemplares similares