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Molecular insight into how the position of an abasic site and its sequence environment influence DNA duplex stability and dynamics

Local perturbations to DNA base-pairing stability from lesions and chemical modifications can alter the stability and dynamics of an entire oligonucleotide. End effects may cause the position of a disruption within a short duplex to influence duplex stability and structural dynamics, yet this aspect...

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Detalles Bibliográficos
Autores principales:	Ashwood, Brennan, Jones, Michael S., Lee, Yumin, Sachleben, Joseph R., Ferguson, Andrew L., Tokmakoff, Andrei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401965/ https://www.ncbi.nlm.nih.gov/pubmed/37546925 http://dx.doi.org/10.1101/2023.07.22.550182

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