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Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer’s Disease

The pathogenesis of Alzheimer’s disease (AD) depends on environmental and heritable factors, with remarkable differences evident between individuals at the molecular level. Here we present a transcriptomic survey of AD using spatial transcriptomics (ST) and single-nucleus RNA-seq in cortical samples...

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Detalles Bibliográficos
Autores principales: Miyoshi, Emily, Morabito, Samuel, Henningfield, Caden M., Rahimzadeh, Negin, Kiani Shabestari, Sepideh, Das, Sudeshna, Michael, Neethu, Reese, Fairlie, Shi, Zechuan, Cao, Zhenkun, Scarfone, Vanessa, Arreola, Miguel A., Lu, Jackie, Wright, Sierra, Silva, Justine, Leavy, Kelsey, Lott, Ira T., Doran, Eric, Yong, William H., Shahin, Saba, Perez-Rosendahl, Mari, Head, Elizabeth, Green, Kim N., Swarup, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402031/
https://www.ncbi.nlm.nih.gov/pubmed/37546983
http://dx.doi.org/10.1101/2023.07.24.550282