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Inhibition of skeletal muscle Lands cycle ameliorates weakness induced by physical inactivity

BACKGROUND: Lipid hydroperoxides (LOOH) have been implicated in skeletal muscle atrophy with age and disuse. Lysophosphatidylcholine acyltransferase 3 (LPCAT3), an enzyme of Lands cycle, conjugates a polyunsaturated fatty acyl chain to a lysophospholipid (PUFA-PL) molecule, providing substrates for...

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Detalles Bibliográficos
Autores principales:	Shahtout, Justin L., Eshima, Hiroaki, Ferrara, Patrick J., Maschek, J. Alan, Cox, James E., Drummond, Micah J., Funai, Katsuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402104/ https://www.ncbi.nlm.nih.gov/pubmed/37546754 http://dx.doi.org/10.1101/2023.07.25.550576

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