Adapting antibacterial display to identify serum active macrocyclic peptide antibiotics

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The lack of available treatments for many antimicrobial resistant infections highlights the critical need for antibiotic discovery innovation. Peptides are an underappreciated antibiotic scaffold because they often suffer from proteolytic instability and toxicity towards human cells, making in vivo...

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Detalles Bibliográficos
Autores principales: Randall, Justin R., Groover, Kyra E., O’Donnell, Angela C., Garza, Joseph M., Cole, T. Jeffrey, Davies, Bryan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402130/
https://www.ncbi.nlm.nih.gov/pubmed/37546850
http://dx.doi.org/10.1101/2023.07.28.550711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402130/
https://www.ncbi.nlm.nih.gov/pubmed/37546850
http://dx.doi.org/10.1101/2023.07.28.550711

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