TGF-β broadly modifies rather than specifically suppresses reactivated memory CD8 T cells in a dose-dependent manner

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Transforming growth factor β (TGF-β) directly acts on naïve, effector and memory T cells to control cell fate decisions, which was shown using genetic abrogation of TGF-β signaling. TGF-β availability is altered by infections and cancer, however the dose-dependent effects of TGF-β on memory CD8 T ce...

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Detalles Bibliográficos
Autores principales: Taber, Alexis, Konecny, Andrew, Scott-Browne, James, Prlic, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402134/
https://www.ncbi.nlm.nih.gov/pubmed/37546887
http://dx.doi.org/10.1101/2023.07.27.550871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402134/
https://www.ncbi.nlm.nih.gov/pubmed/37546887
http://dx.doi.org/10.1101/2023.07.27.550871

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