Efficient Formation of Single-copy Human Artificial Chromosomes

Large DNA assembly methodologies underlie milestone achievements in synthetic prokaryotic and budding yeast chromosomes. While budding yeast control chromosome inheritance through ~125 bp DNA sequence-defined centromeres, mammals and many other eukaryotes use large, epigenetic centromeres. Harnessin...

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Detalles Bibliográficos
Autores principales: Gambogi, Craig W., Mer, Elie, Brown, David M., Yankson, George, Gavade, Janardan N., Logsdon, Glennis A., Heun, Patrick, Glass, John I., Black, Ben E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402137/
https://www.ncbi.nlm.nih.gov/pubmed/37546784
http://dx.doi.org/10.1101/2023.06.30.547284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402137/
https://www.ncbi.nlm.nih.gov/pubmed/37546784
http://dx.doi.org/10.1101/2023.06.30.547284

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