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Efficient Formation of Single-copy Human Artificial Chromosomes

Large DNA assembly methodologies underlie milestone achievements in synthetic prokaryotic and budding yeast chromosomes. While budding yeast control chromosome inheritance through ~125 bp DNA sequence-defined centromeres, mammals and many other eukaryotes use large, epigenetic centromeres. Harnessin...

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Detalles Bibliográficos
Autores principales:	Gambogi, Craig W., Mer, Elie, Brown, David M., Yankson, George, Gavade, Janardan N., Logsdon, Glennis A., Heun, Patrick, Glass, John I., Black, Ben E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402137/ https://www.ncbi.nlm.nih.gov/pubmed/37546784 http://dx.doi.org/10.1101/2023.06.30.547284

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