Cargando…
Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles
Microglia are resident immune cells of the brain that play important roles in mediating inflammatory responses in several neurological diseases via direct and indirect mechanisms. One indirect mechanism may involve extracellular vesicle (EV) release, so that the molecular cargo transported by microg...
Autores principales: | Santiago, Juliet V., Natu, Aditya, Ramelow, Christina C., Rayaprolu, Sruti, Xiao, Hailian, Kumar, Vishnu, Seyfried, Nicholas T., Rangaraju, Srikant |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402142/ https://www.ncbi.nlm.nih.gov/pubmed/37546899 http://dx.doi.org/10.1101/2023.07.28.551012 |
Ejemplares similares
-
Cellular Proteomic Profiling Using Proximity Labeling by TurboID-NES in Microglial and Neuronal Cell Lines
por: Sunna, Sydney, et al.
Publicado: (2023) -
Systems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tau
por: Rayaprolu, Sruti, et al.
Publicado: (2020) -
Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain
por: Rayaprolu, Sruti, et al.
Publicado: (2022) -
Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms
por: Nelson, Ruth S., et al.
Publicado: (2022) -
Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer’s disease
por: Rayaprolu, Sruti, et al.
Publicado: (2020)