Cross-site reproducibility of human cortical organoids reveals consistent cell type composition and architecture

BACKGROUND: Reproducibility of human cortical organoid (hCO) phenotypes remains a concern for modeling neurodevelopmental disorders. While guided hCO protocols reproducibly generate cortical cell types in multiple cell lines at one site, variability across sites using a harmonized protocol has not y...

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Detalles Bibliográficos
Autores principales: Glass, Madison R, Waxman, Elisa A., Yamashita, Satoshi, Lafferty, Michael, Beltran, Alvaro, Farah, Tala, Patel, Niyanta K, Matoba, Nana, Ahmed, Sara, Srivastava, Mary, Drake, Emma, Davis, Liam T., Yeturi, Meghana, Sun, Kexin, Love, Michael I., Hashimoto-Torii, Kazue, French, Deborah L., Stein, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402155/
https://www.ncbi.nlm.nih.gov/pubmed/37546772
http://dx.doi.org/10.1101/2023.07.28.550873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402155/
https://www.ncbi.nlm.nih.gov/pubmed/37546772
http://dx.doi.org/10.1101/2023.07.28.550873

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