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Cross-site reproducibility of human cortical organoids reveals consistent cell type composition and architecture
BACKGROUND: Reproducibility of human cortical organoid (hCO) phenotypes remains a concern for modeling neurodevelopmental disorders. While guided hCO protocols reproducibly generate cortical cell types in multiple cell lines at one site, variability across sites using a harmonized protocol has not y...
Autores principales: | Glass, Madison R, Waxman, Elisa A., Yamashita, Satoshi, Lafferty, Michael, Beltran, Alvaro, Farah, Tala, Patel, Niyanta K, Matoba, Nana, Ahmed, Sara, Srivastava, Mary, Drake, Emma, Davis, Liam T., Yeturi, Meghana, Sun, Kexin, Love, Michael I., Hashimoto-Torii, Kazue, French, Deborah L., Stein, Jason L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402155/ https://www.ncbi.nlm.nih.gov/pubmed/37546772 http://dx.doi.org/10.1101/2023.07.28.550873 |
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