Schnurri-3 inhibition rescues skeletal fragility and vascular skeletal stem cell niche pathology in a mouse model of osteogenesis imperfecta

Osteogenesis imperfecta (OI) is a disorder of low bone mass and increased fracture risk due to a range of genetic variants that prominently include mutations in genes encoding type collagen. While it is well known that OI reflects defects in the activity of bone-forming osteoblasts, it is currently...

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Detalles Bibliográficos
Autores principales: Xu, Ren, Li, Na, Shi, Baohong, Li, Zan, Han, Jie, Sun, Jun, Yallowitz, Alisha, Bok, Seoyeon, Xiao, Shuang, Wu, Zouxing, Chen, Yu, Xu, Yan, Qin, Tian, Lin, Zhiming, Zheng, Haiping, Shen, Rong, Greenblatt, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402191/
https://www.ncbi.nlm.nih.gov/pubmed/37546916
http://dx.doi.org/10.21203/rs.3.rs-3153957/v1

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