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CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles

Visceral leishmaniasis, caused by Leishmania donovani, is a life-threatening parasitic disease, but current antileishmanial drugs are limited and have severe drawbacks. There have been efforts to repurpose antifungal azole drugs for the treatment of Leishmania infection. Antifungal azoles are known...

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Detalles Bibliográficos
Autores principales:	Jin, Yiru, Basu, Somrita, Feng, Mei, Ning, Yu, Munasinghe, Indeewara, Joachim, Arline M., Li, Junan, Madden, Robert, Burks, Hannah, Gao, Philip, Perera, Chamani, Werbovetz, Karl A., Zhang, Kai, Wang, Michael Zhuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402201/ https://www.ncbi.nlm.nih.gov/pubmed/37546914 http://dx.doi.org/10.21203/rs.3.rs-3185204/v1

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