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Generation and characterization of a zebrafish knockout model of abcb4, a homolog of the human multidrug efflux transporter P-glycoprotein

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The ATP-binding cassette subfamily B member 1 (ABCB1), encoding a multidrug transporter referred to as P-glycoprotein (Pgp), plays a critical role in the efflux of xenobiotics in humans and is implicated in cancer resistance to chemotherapy. Therefore, developing high throughput animal models to scr...

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Detalles Bibliográficos
Autores principales:	Park, Jinhee, Kim, Hyosung, alabdalla, Leen, Mishra, Smriti, Mchaourab, Hassane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402247/ https://www.ncbi.nlm.nih.gov/pubmed/37546821 http://dx.doi.org/10.21203/rs.3.rs-3192988/v1

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