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Single Protein Encapsulated SN38 for Tumor-Targeting Treatment

BACKGROUND: The alkaloid camptothecin analog SN38 is a potent antineoplastic agent, but cannot be used directly for clinical application due to its poor water solubility. Currently, the prodrug approach on SN38 has resulted in 3 FDA-approved cancer therapeutics, irinotecan, ONIVYDE, and Trodelvy. Ho...

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Detalles Bibliográficos
Autores principales:	Yu, Changjun J., Huang, Faqing, Wang, Kinsley, Liu, Mengmeng, Chow, Warren A., Ling, Xiang, Li, Fengzhi, Causey, Jason L., Huang, Xiuzhen, Cook-Wiens, Galen, Cui, Xiaojiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402254/ https://www.ncbi.nlm.nih.gov/pubmed/37546894 http://dx.doi.org/10.21203/rs.3.rs-3154635/v1

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