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SYST-14 D2C7 CAR EFFECTIVELY AND SAFELY TREATS EGFRWT AND EGFRVIII-EXPRESSING TUMORS FOLLOWING INTRACRANIAL ADMINISTRATION

Glioblastoma (GBM) is the most aggressive primary brain cancer with a median survival of less than 16 months. Therefore, significant treatment advances are of critical need. Immunotherapies, such as chimeric antigen receptor (CAR) T cells, have achieved remarkable success in eliminating hematologica...

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Detalles Bibliográficos
Autores principales: Wilkinson, Daniel, Wilson, Joseph, Lerner, Emily, Ryan, Katherine, Chandramohan, Vidyalakshmi, Landi, Daniel, Bigner, Darell, Fecci, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402302/
http://dx.doi.org/10.1093/noajnl/vdad070.118