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CLRM-10 ENHANCED PATIENT CARE FOR BRAIN METASTASIS PATIENTS UTILIZING A DEDICATED METASTASIS TUMOR BOARD

BACKGROUND: Patients with brain metastases are a heterogeneous population. In contrast to patients with primary brain tumors, these patients require individualized therapy based on the type and status of systemic cancer, number and volume of brain metastases, anticipated efficacy of therapy and surv...

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Autores principales: Rogers, Lisa, Robin, Adam, Shah, Mira, Siddiqui, Salim, Snyder, Jim, Walbert, Tobias, Lee, Ian, MIkkelsen, Tom, Rock, Jack, Scarpace, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402398/
http://dx.doi.org/10.1093/noajnl/vdad070.032
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author Rogers, Lisa
Robin, Adam
Shah, Mira
Siddiqui, Salim
Snyder, Jim
Walbert, Tobias
Lee, Ian
MIkkelsen, Tom
Rock, Jack
Scarpace, Lisa
author_facet Rogers, Lisa
Robin, Adam
Shah, Mira
Siddiqui, Salim
Snyder, Jim
Walbert, Tobias
Lee, Ian
MIkkelsen, Tom
Rock, Jack
Scarpace, Lisa
author_sort Rogers, Lisa
collection PubMed
description BACKGROUND: Patients with brain metastases are a heterogeneous population. In contrast to patients with primary brain tumors, these patients require individualized therapy based on the type and status of systemic cancer, number and volume of brain metastases, anticipated efficacy of therapy and survival. Therapeutic options for brain metastasis; surgical, radiation and precision medicine approaches have increased in recent years as has survival for a number of cancers, leading to more sophisticated care. To meet this challenge in January 2023 we organized a dedicated brain metastasis tumor board. METHODS: We reviewed the number of total patients, and those newly-diagnosed, presented at the dedicated brain metastasis board in the first 10 weeks of 2023 as compared with the same time interval the prior year where similar cases were presented at a general brain tumor board. We also assessed change in practice pattern based on the dedicated metastasis tumor board. RESULTS: 89 patients were presented in the first 10 weeks of 2023, including 75 who were newly diagnosed. The total number and those newly diagnosed are 17% higher than the prior year. The dedicated brain metastasis board, staffed by experts in brain metastases, allowed for earlier identification of patients eligible for clinical trial and additionally our review of patients identified the need for standardizing advanced imaging techniques including high resolution, higher contrast-dose MRI scans for better assessment of brain metastases across our hospital sites. CONCLUSION: We found that a dedicated brain metastasis board increased the number of patients presented for multidisciplinary review, including new patients, which served to better identify those eligible for clinical trial. It led to a consensus to incorporate advanced imaging techniques for assessing treatment response. The experience is superior to inclusion of these patients in a general brain tumor board.
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spelling pubmed-104023982023-08-05 CLRM-10 ENHANCED PATIENT CARE FOR BRAIN METASTASIS PATIENTS UTILIZING A DEDICATED METASTASIS TUMOR BOARD Rogers, Lisa Robin, Adam Shah, Mira Siddiqui, Salim Snyder, Jim Walbert, Tobias Lee, Ian MIkkelsen, Tom Rock, Jack Scarpace, Lisa Neurooncol Adv Final Category: Clinical Research Methods BACKGROUND: Patients with brain metastases are a heterogeneous population. In contrast to patients with primary brain tumors, these patients require individualized therapy based on the type and status of systemic cancer, number and volume of brain metastases, anticipated efficacy of therapy and survival. Therapeutic options for brain metastasis; surgical, radiation and precision medicine approaches have increased in recent years as has survival for a number of cancers, leading to more sophisticated care. To meet this challenge in January 2023 we organized a dedicated brain metastasis tumor board. METHODS: We reviewed the number of total patients, and those newly-diagnosed, presented at the dedicated brain metastasis board in the first 10 weeks of 2023 as compared with the same time interval the prior year where similar cases were presented at a general brain tumor board. We also assessed change in practice pattern based on the dedicated metastasis tumor board. RESULTS: 89 patients were presented in the first 10 weeks of 2023, including 75 who were newly diagnosed. The total number and those newly diagnosed are 17% higher than the prior year. The dedicated brain metastasis board, staffed by experts in brain metastases, allowed for earlier identification of patients eligible for clinical trial and additionally our review of patients identified the need for standardizing advanced imaging techniques including high resolution, higher contrast-dose MRI scans for better assessment of brain metastases across our hospital sites. CONCLUSION: We found that a dedicated brain metastasis board increased the number of patients presented for multidisciplinary review, including new patients, which served to better identify those eligible for clinical trial. It led to a consensus to incorporate advanced imaging techniques for assessing treatment response. The experience is superior to inclusion of these patients in a general brain tumor board. Oxford University Press 2023-08-04 /pmc/articles/PMC10402398/ http://dx.doi.org/10.1093/noajnl/vdad070.032 Text en © The Author(s) 2023. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Final Category: Clinical Research Methods
Rogers, Lisa
Robin, Adam
Shah, Mira
Siddiqui, Salim
Snyder, Jim
Walbert, Tobias
Lee, Ian
MIkkelsen, Tom
Rock, Jack
Scarpace, Lisa
CLRM-10 ENHANCED PATIENT CARE FOR BRAIN METASTASIS PATIENTS UTILIZING A DEDICATED METASTASIS TUMOR BOARD
title CLRM-10 ENHANCED PATIENT CARE FOR BRAIN METASTASIS PATIENTS UTILIZING A DEDICATED METASTASIS TUMOR BOARD
title_full CLRM-10 ENHANCED PATIENT CARE FOR BRAIN METASTASIS PATIENTS UTILIZING A DEDICATED METASTASIS TUMOR BOARD
title_fullStr CLRM-10 ENHANCED PATIENT CARE FOR BRAIN METASTASIS PATIENTS UTILIZING A DEDICATED METASTASIS TUMOR BOARD
title_full_unstemmed CLRM-10 ENHANCED PATIENT CARE FOR BRAIN METASTASIS PATIENTS UTILIZING A DEDICATED METASTASIS TUMOR BOARD
title_short CLRM-10 ENHANCED PATIENT CARE FOR BRAIN METASTASIS PATIENTS UTILIZING A DEDICATED METASTASIS TUMOR BOARD
title_sort clrm-10 enhanced patient care for brain metastasis patients utilizing a dedicated metastasis tumor board
topic Final Category: Clinical Research Methods
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402398/
http://dx.doi.org/10.1093/noajnl/vdad070.032
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