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TIPS-04 A RANDOMIZED, MULTI-INSTITUTIONAL PILOT STUDY TO EVALUATE THE MOLECULAR AND CELLULAR RESPONSE TO TREATMENT WITH NIVOLUMAB WITH EITHER ADJUVANT IPILIMUMAB OR RELATLIMAB IN ADULT PATIENTS WITH SURGICALLY RESECTABLE MELANOMA BRAIN METASTASES: ONGOING TRIAL
BACKGROUND: Melanoma brain metastases (MBM) is a major cause of morbidity and mortality. The way melanoma malignant cells interact with the microenvironment in distal sites including the brain, plays a major role in tumorigenesis, metastasis, and tumor survival. Data supports the tumor microenvironm...
Autores principales: | Pina, Yolanda, Chen, Ann, Tran, Nam, Etame, Arnold, Liu, James, Furlan, Andre Beer, Mokhtari, Sepideh, Peguero, Edwin, Li, Jiannong, Law, Vincent, Khushalani, Nikhil, Smalley, Inna, Vogelbaum, Michael, Yu, Michael, Arrington, John, Macaulay, Robert, Tawbi, Hussein, Smalley, Keiran, Forsyth, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402413/ http://dx.doi.org/10.1093/noajnl/vdad070.135 |
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