Cargando…

NEIM-08 MODELING COMPETITION BETWEEN SUBPOPULATIONS WITH VARIABLE DNA CONTENT IN RESOURCE LIMITED MICROENVIRONMENTS

Resource limitations shape the outcome of competitions between heterogeneous pre-malignant cells. One example of such heterogeneity is in the ploidy (DNA content) of pre-malignant cells. High-ploidy cells need more resources, to synthesize increasing amounts of DNA, RNA and proteins. To model how su...

Descripción completa

Detalles Bibliográficos
Autores principales: Katira, Parag, Rentzeperis, Frederika, Beck, Richard, Pinto, Ana Forero, Nowicka, Zuzanna, Tagal, Vural, Teer, Jamie, Scanu, Elisa, Pasetto, Stefano, Veith, Thomas, Fiandaca, Giada, Fritz, Yi, Devine, Karen, Barnholtz-Sloan, Jill, Farinhas, Joaquim, Gomes, Ana, Andor, Noemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402424/
http://dx.doi.org/10.1093/noajnl/vdad070.059