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TIPS-23 SAFETY AND FEASIBILITY RESULTS FROM A PHASE 1/2 CLINICAL TRIAL OF RHENIUM (186RE) OBISBEMEDA (186RNL) IN RECURRENT GLIOMA: THE RESPECT-GBM TRIAL

OBJECTIVES: 186RNL is BMEDA-chelated 186Re encapsulated in nanoliposomes. 186Re’s ~2 mm beta emission path length provides direct delivery of radiation therapy while sparing surrounding healthy tissue. 186RNL is delivered via convection enhanced delivery (CED) to achieve durable, localized tumor ret...

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Detalles Bibliográficos
Autores principales:	Brenner, Andrew, Patel, Toral, Youssef, Michael, Bao, Ande, Phillips, William, Hedrick, Marc, Moore, Melissa, LaFrance, Norman, Weinberg, Jeffrey, Floyd, John, Michalek, Joel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Final Category: Trials in Progress
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402450/ http://dx.doi.org/10.1093/noajnl/vdad070.153

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