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Evaluation of L-Carnitine Potential in Improvement of Male Fertility

L-carnitine, through its antioxidant potential, plays a significant role in reducing ROS production in male genital tract; therefore, fundamental improvements in spermatogenesis process and sperm structural and functional parameters in seminal plasma can be observed by treatment with L-carnitine. A...

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Detalles Bibliográficos
Autores principales: Kooshesh, Leila, Nateghian, Zohre, Aliabadi, Elham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402461/
https://www.ncbi.nlm.nih.gov/pubmed/37547570
http://dx.doi.org/10.18502/jri.v24i2.12491
Descripción
Sumario:L-carnitine, through its antioxidant potential, plays a significant role in reducing ROS production in male genital tract; therefore, fundamental improvements in spermatogenesis process and sperm structural and functional parameters in seminal plasma can be observed by treatment with L-carnitine. A literature search was performed using PubMed (including Medline) from the database earliest inception to 2021. Eligibility criteria included studies on protective effects of L-carnitine against damages to the male reproductive system. Based on the findings of the current study, L-carnitine has an effective potential to protect testis and improve conventional and functional sperm parameters against ROS-induced damages by sperm cryopreservation, busulfan treatment, and radiation.