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A methodology for incorporating a photon‐counting CT system into routine clinical use
Photon‐counting computed tomography (PCCT) systems are increasingly available in the U.S. following Food and Drug Administration (FDA) approval of the first clinical PCCT system in Fall 2021. Consequently, there will be a need to incorporate PCCTs into existing fleets of traditional CT systems. The...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402682/ https://www.ncbi.nlm.nih.gov/pubmed/37389963 http://dx.doi.org/10.1002/acm2.14069 |
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author | Bache, Steven T. Samei, Ehsan |
author_facet | Bache, Steven T. Samei, Ehsan |
author_sort | Bache, Steven T. |
collection | PubMed |
description | Photon‐counting computed tomography (PCCT) systems are increasingly available in the U.S. following Food and Drug Administration (FDA) approval of the first clinical PCCT system in Fall 2021. Consequently, there will be a need to incorporate PCCTs into existing fleets of traditional CT systems. The commissioning process of a PCCT was devised by evaluating the degree of agreement between the performance of the PCCT and that of established clinical CT systems. A PCCT system (Siemens NAEOTOM Alpha) was evaluated using the American College of Radiology(ACR) CT phantom (Gammex 464). The phantom was scanned on the system and on a 3rd Generation EID CT system (Siemens Force) at three clinical dose levels. Images were reconstructed across the range of available reconstruction kernels and Iterative Reconstruction (IR) strengths. Two image quality metrics—spatial resolution and noise texture—were calculated using AAPM TG233 software (imQuest), as well as a dose metric to achieve target image noise magnitude of 10 HU. For each pair of EID‐PCCT kernel/IR strengths, the difference in metrics were calculated, weighted, and multiplied over all metrics to determine the concordance between systems. IR performance was characterized by comparing relative noise texture and reference dose as a function of IR strength for each system. In general, as kernel “sharpness” increased for each system, spatial resolution, noise spatial frequency, and reference dose increased. For a given kernel, EID reconstruction showed higher spatial resolution compared to PCCT in standard resolution mode. PCCT implementation of IR better preserved noise texture across all strengths compared to the EID, demonstrated by respective 20 and 7% shifts in noise texture from IR “Off” to IR “Max.” Overall, the closest match for a given EID reconstruction kernel/IR strength was identified as a PCCT kernel with “sharpness” increased by 1 step and IR strength increased by 1–2 steps. Substantial dose reduction potential of up to 70% was found when targeting a constant noise magnitude. |
format | Online Article Text |
id | pubmed-10402682 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104026822023-08-05 A methodology for incorporating a photon‐counting CT system into routine clinical use Bache, Steven T. Samei, Ehsan J Appl Clin Med Phys Medical Imaging Photon‐counting computed tomography (PCCT) systems are increasingly available in the U.S. following Food and Drug Administration (FDA) approval of the first clinical PCCT system in Fall 2021. Consequently, there will be a need to incorporate PCCTs into existing fleets of traditional CT systems. The commissioning process of a PCCT was devised by evaluating the degree of agreement between the performance of the PCCT and that of established clinical CT systems. A PCCT system (Siemens NAEOTOM Alpha) was evaluated using the American College of Radiology(ACR) CT phantom (Gammex 464). The phantom was scanned on the system and on a 3rd Generation EID CT system (Siemens Force) at three clinical dose levels. Images were reconstructed across the range of available reconstruction kernels and Iterative Reconstruction (IR) strengths. Two image quality metrics—spatial resolution and noise texture—were calculated using AAPM TG233 software (imQuest), as well as a dose metric to achieve target image noise magnitude of 10 HU. For each pair of EID‐PCCT kernel/IR strengths, the difference in metrics were calculated, weighted, and multiplied over all metrics to determine the concordance between systems. IR performance was characterized by comparing relative noise texture and reference dose as a function of IR strength for each system. In general, as kernel “sharpness” increased for each system, spatial resolution, noise spatial frequency, and reference dose increased. For a given kernel, EID reconstruction showed higher spatial resolution compared to PCCT in standard resolution mode. PCCT implementation of IR better preserved noise texture across all strengths compared to the EID, demonstrated by respective 20 and 7% shifts in noise texture from IR “Off” to IR “Max.” Overall, the closest match for a given EID reconstruction kernel/IR strength was identified as a PCCT kernel with “sharpness” increased by 1 step and IR strength increased by 1–2 steps. Substantial dose reduction potential of up to 70% was found when targeting a constant noise magnitude. John Wiley and Sons Inc. 2023-06-30 /pmc/articles/PMC10402682/ /pubmed/37389963 http://dx.doi.org/10.1002/acm2.14069 Text en © 2023 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Medical Imaging Bache, Steven T. Samei, Ehsan A methodology for incorporating a photon‐counting CT system into routine clinical use |
title | A methodology for incorporating a photon‐counting CT system into routine clinical use |
title_full | A methodology for incorporating a photon‐counting CT system into routine clinical use |
title_fullStr | A methodology for incorporating a photon‐counting CT system into routine clinical use |
title_full_unstemmed | A methodology for incorporating a photon‐counting CT system into routine clinical use |
title_short | A methodology for incorporating a photon‐counting CT system into routine clinical use |
title_sort | methodology for incorporating a photon‐counting ct system into routine clinical use |
topic | Medical Imaging |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402682/ https://www.ncbi.nlm.nih.gov/pubmed/37389963 http://dx.doi.org/10.1002/acm2.14069 |
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