Cargando…

A methodology for incorporating a photon‐counting CT system into routine clinical use

Photon‐counting computed tomography (PCCT) systems are increasingly available in the U.S. following Food and Drug Administration (FDA) approval of the first clinical PCCT system in Fall 2021. Consequently, there will be a need to incorporate PCCTs into existing fleets of traditional CT systems. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Bache, Steven T., Samei, Ehsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402682/
https://www.ncbi.nlm.nih.gov/pubmed/37389963
http://dx.doi.org/10.1002/acm2.14069
_version_ 1785084896778125312
author Bache, Steven T.
Samei, Ehsan
author_facet Bache, Steven T.
Samei, Ehsan
author_sort Bache, Steven T.
collection PubMed
description Photon‐counting computed tomography (PCCT) systems are increasingly available in the U.S. following Food and Drug Administration (FDA) approval of the first clinical PCCT system in Fall 2021. Consequently, there will be a need to incorporate PCCTs into existing fleets of traditional CT systems. The commissioning process of a PCCT was devised by evaluating the degree of agreement between the performance of the PCCT and that of established clinical CT systems. A PCCT system (Siemens NAEOTOM Alpha) was evaluated using the American College of Radiology(ACR) CT phantom (Gammex 464). The phantom was scanned on the system and on a 3rd Generation EID CT system (Siemens Force) at three clinical dose levels. Images were reconstructed across the range of available reconstruction kernels and Iterative Reconstruction (IR) strengths. Two image quality metrics—spatial resolution and noise texture—were calculated using AAPM TG233 software (imQuest), as well as a dose metric to achieve target image noise magnitude of 10 HU. For each pair of EID‐PCCT kernel/IR strengths, the difference in metrics were calculated, weighted, and multiplied over all metrics to determine the concordance between systems. IR performance was characterized by comparing relative noise texture and reference dose as a function of IR strength for each system. In general, as kernel “sharpness” increased for each system, spatial resolution, noise spatial frequency, and reference dose increased. For a given kernel, EID reconstruction showed higher spatial resolution compared to PCCT in standard resolution mode. PCCT implementation of IR better preserved noise texture across all strengths compared to the EID, demonstrated by respective 20 and 7% shifts in noise texture from IR “Off” to IR “Max.” Overall, the closest match for a given EID reconstruction kernel/IR strength was identified as a PCCT kernel with “sharpness” increased by 1 step and IR strength increased by 1–2 steps. Substantial dose reduction potential of up to 70% was found when targeting a constant noise magnitude.
format Online
Article
Text
id pubmed-10402682
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-104026822023-08-05 A methodology for incorporating a photon‐counting CT system into routine clinical use Bache, Steven T. Samei, Ehsan J Appl Clin Med Phys Medical Imaging Photon‐counting computed tomography (PCCT) systems are increasingly available in the U.S. following Food and Drug Administration (FDA) approval of the first clinical PCCT system in Fall 2021. Consequently, there will be a need to incorporate PCCTs into existing fleets of traditional CT systems. The commissioning process of a PCCT was devised by evaluating the degree of agreement between the performance of the PCCT and that of established clinical CT systems. A PCCT system (Siemens NAEOTOM Alpha) was evaluated using the American College of Radiology(ACR) CT phantom (Gammex 464). The phantom was scanned on the system and on a 3rd Generation EID CT system (Siemens Force) at three clinical dose levels. Images were reconstructed across the range of available reconstruction kernels and Iterative Reconstruction (IR) strengths. Two image quality metrics—spatial resolution and noise texture—were calculated using AAPM TG233 software (imQuest), as well as a dose metric to achieve target image noise magnitude of 10 HU. For each pair of EID‐PCCT kernel/IR strengths, the difference in metrics were calculated, weighted, and multiplied over all metrics to determine the concordance between systems. IR performance was characterized by comparing relative noise texture and reference dose as a function of IR strength for each system. In general, as kernel “sharpness” increased for each system, spatial resolution, noise spatial frequency, and reference dose increased. For a given kernel, EID reconstruction showed higher spatial resolution compared to PCCT in standard resolution mode. PCCT implementation of IR better preserved noise texture across all strengths compared to the EID, demonstrated by respective 20 and 7% shifts in noise texture from IR “Off” to IR “Max.” Overall, the closest match for a given EID reconstruction kernel/IR strength was identified as a PCCT kernel with “sharpness” increased by 1 step and IR strength increased by 1–2 steps. Substantial dose reduction potential of up to 70% was found when targeting a constant noise magnitude. John Wiley and Sons Inc. 2023-06-30 /pmc/articles/PMC10402682/ /pubmed/37389963 http://dx.doi.org/10.1002/acm2.14069 Text en © 2023 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Medical Imaging
Bache, Steven T.
Samei, Ehsan
A methodology for incorporating a photon‐counting CT system into routine clinical use
title A methodology for incorporating a photon‐counting CT system into routine clinical use
title_full A methodology for incorporating a photon‐counting CT system into routine clinical use
title_fullStr A methodology for incorporating a photon‐counting CT system into routine clinical use
title_full_unstemmed A methodology for incorporating a photon‐counting CT system into routine clinical use
title_short A methodology for incorporating a photon‐counting CT system into routine clinical use
title_sort methodology for incorporating a photon‐counting ct system into routine clinical use
topic Medical Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402682/
https://www.ncbi.nlm.nih.gov/pubmed/37389963
http://dx.doi.org/10.1002/acm2.14069
work_keys_str_mv AT bachestevent amethodologyforincorporatingaphotoncountingctsystemintoroutineclinicaluse
AT sameiehsan amethodologyforincorporatingaphotoncountingctsystemintoroutineclinicaluse
AT bachestevent methodologyforincorporatingaphotoncountingctsystemintoroutineclinicaluse
AT sameiehsan methodologyforincorporatingaphotoncountingctsystemintoroutineclinicaluse