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Prevalence of Glaucoma Following Paediatric Cataract Surgery in an Australian Tertiary Referral Centre

PURPOSE: Secondary glaucoma following childhood cataract surgery remains the most common complication in the paediatric population. This study aimed to determine the incidence, time to progression and risk factors associated with the development of secondary glaucoma following childhood cataract sur...

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Autores principales: Wood, Alanna, Lim, Benjamin, Matthews, Jim, Karaconji, Tanya, Zagora, Sophia L, Jamieson, Robyn V, Grigg, John R, Jones, Michael, Rowe, Neil, Hing, Stephen, Donaldson, Craig, Smith, James E H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402721/
https://www.ncbi.nlm.nih.gov/pubmed/37547173
http://dx.doi.org/10.2147/OPTH.S400512
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author Wood, Alanna
Lim, Benjamin
Matthews, Jim
Karaconji, Tanya
Zagora, Sophia L
Jamieson, Robyn V
Grigg, John R
Jones, Michael
Rowe, Neil
Hing, Stephen
Donaldson, Craig
Smith, James E H
author_facet Wood, Alanna
Lim, Benjamin
Matthews, Jim
Karaconji, Tanya
Zagora, Sophia L
Jamieson, Robyn V
Grigg, John R
Jones, Michael
Rowe, Neil
Hing, Stephen
Donaldson, Craig
Smith, James E H
author_sort Wood, Alanna
collection PubMed
description PURPOSE: Secondary glaucoma following childhood cataract surgery remains the most common complication in the paediatric population. This study aimed to determine the incidence, time to progression and risk factors associated with the development of secondary glaucoma following childhood cataract surgery in a paediatric population. Outcome measures were the detection of secondary glaucoma, postoperative time frame to development of glaucoma and risk factors in its development. PATIENTS AND METHODS: A retrospective case series was conducted between 2003 and 2017 at a tertiary children’s hospital in Sydney. The patient population included those 16 years or less of age who underwent congenital cataract extraction, with or without an intraocular lens implantation and who had been followed up for a minimum of six months following surgery. Patients were excluded if they had cataract aetiology other than congenital idiopathic cataract. Multivariate Cox Regression analysis was used to determine relevant risk factors. RESULTS: A total of 320 eyes in 216 patients were included in the study. Secondary glaucoma developed in 11.9% of eyes. In those that developed secondary glaucoma, the average time to onset from surgery was 3.2 years (median 2.75 years). The mean age of diagnosis of secondary glaucoma was 4.58 years (median 3.5 years, range 2.5 months to 13.23 years). Microcornea was the only adverse characteristic significantly associated with an increased risk of secondary glaucoma (HR 6.30, p 0.003). CONCLUSION: Despite modern surgical techniques, glaucoma remains a significant long-term sequela in children following cataract surgery.
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spelling pubmed-104027212023-08-05 Prevalence of Glaucoma Following Paediatric Cataract Surgery in an Australian Tertiary Referral Centre Wood, Alanna Lim, Benjamin Matthews, Jim Karaconji, Tanya Zagora, Sophia L Jamieson, Robyn V Grigg, John R Jones, Michael Rowe, Neil Hing, Stephen Donaldson, Craig Smith, James E H Clin Ophthalmol Original Research PURPOSE: Secondary glaucoma following childhood cataract surgery remains the most common complication in the paediatric population. This study aimed to determine the incidence, time to progression and risk factors associated with the development of secondary glaucoma following childhood cataract surgery in a paediatric population. Outcome measures were the detection of secondary glaucoma, postoperative time frame to development of glaucoma and risk factors in its development. PATIENTS AND METHODS: A retrospective case series was conducted between 2003 and 2017 at a tertiary children’s hospital in Sydney. The patient population included those 16 years or less of age who underwent congenital cataract extraction, with or without an intraocular lens implantation and who had been followed up for a minimum of six months following surgery. Patients were excluded if they had cataract aetiology other than congenital idiopathic cataract. Multivariate Cox Regression analysis was used to determine relevant risk factors. RESULTS: A total of 320 eyes in 216 patients were included in the study. Secondary glaucoma developed in 11.9% of eyes. In those that developed secondary glaucoma, the average time to onset from surgery was 3.2 years (median 2.75 years). The mean age of diagnosis of secondary glaucoma was 4.58 years (median 3.5 years, range 2.5 months to 13.23 years). Microcornea was the only adverse characteristic significantly associated with an increased risk of secondary glaucoma (HR 6.30, p 0.003). CONCLUSION: Despite modern surgical techniques, glaucoma remains a significant long-term sequela in children following cataract surgery. Dove 2023-07-31 /pmc/articles/PMC10402721/ /pubmed/37547173 http://dx.doi.org/10.2147/OPTH.S400512 Text en © 2023 Wood et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Wood, Alanna
Lim, Benjamin
Matthews, Jim
Karaconji, Tanya
Zagora, Sophia L
Jamieson, Robyn V
Grigg, John R
Jones, Michael
Rowe, Neil
Hing, Stephen
Donaldson, Craig
Smith, James E H
Prevalence of Glaucoma Following Paediatric Cataract Surgery in an Australian Tertiary Referral Centre
title Prevalence of Glaucoma Following Paediatric Cataract Surgery in an Australian Tertiary Referral Centre
title_full Prevalence of Glaucoma Following Paediatric Cataract Surgery in an Australian Tertiary Referral Centre
title_fullStr Prevalence of Glaucoma Following Paediatric Cataract Surgery in an Australian Tertiary Referral Centre
title_full_unstemmed Prevalence of Glaucoma Following Paediatric Cataract Surgery in an Australian Tertiary Referral Centre
title_short Prevalence of Glaucoma Following Paediatric Cataract Surgery in an Australian Tertiary Referral Centre
title_sort prevalence of glaucoma following paediatric cataract surgery in an australian tertiary referral centre
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402721/
https://www.ncbi.nlm.nih.gov/pubmed/37547173
http://dx.doi.org/10.2147/OPTH.S400512
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