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Nutritional vitamin D supplementation in chronic hemodialysis: An uncontrolled open-label trial

The present study was evaluated by the incidence of vitamin D deficiency and management of hemodialysis (HD) patients with low doses of vitamin D over 6 months. This uncontrolled open-label trial was fulfilled in descriptive and then analytical phases from 2008 to 2010 recruiting chronic HD patients...

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Autores principales: Shahidi, Shahrzad, Mortazavi, Mojgan, Bakhtiari, Mina Bakhshali, Mirhoseini, Mohammad Sajjad, Ghasemi, Golsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402799/
https://www.ncbi.nlm.nih.gov/pubmed/37546001
http://dx.doi.org/10.4103/jehp.jehp_1507_22
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author Shahidi, Shahrzad
Mortazavi, Mojgan
Bakhtiari, Mina Bakhshali
Mirhoseini, Mohammad Sajjad
Ghasemi, Golsa
author_facet Shahidi, Shahrzad
Mortazavi, Mojgan
Bakhtiari, Mina Bakhshali
Mirhoseini, Mohammad Sajjad
Ghasemi, Golsa
author_sort Shahidi, Shahrzad
collection PubMed
description The present study was evaluated by the incidence of vitamin D deficiency and management of hemodialysis (HD) patients with low doses of vitamin D over 6 months. This uncontrolled open-label trial was fulfilled in descriptive and then analytical phases from 2008 to 2010 recruiting chronic HD patients in our province. For this purpose, 169 patients undergoing regular HD were randomly selected and their vitamin D level was measured. Then, 54 patients with vitamin D levels less than 30 ng/mL entered the second phase. This group received 50,000 IU vitamin D3 monthly for 6 months. The mean vitamin D level in 169 patients was 21.73 ± 20.27 ng/mL. As well, 62.7% had vitamin D levels less than 30 ng/mL. Following the six-month intervention, mean vitamin D levels elevated significantly from 17.03 ± 7.4 to 42.8 ± 16.9 ng/mL (P < .0001). In this study, the incidence rate of vitamin D deficiency was 62.7%, lower than that in previous research in patients undergoing chronic HD. Vitamin D3 administration at lower doses than healthy people could significantly increase vitamin D level.
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spelling pubmed-104027992023-08-05 Nutritional vitamin D supplementation in chronic hemodialysis: An uncontrolled open-label trial Shahidi, Shahrzad Mortazavi, Mojgan Bakhtiari, Mina Bakhshali Mirhoseini, Mohammad Sajjad Ghasemi, Golsa J Educ Health Promot Brief Report The present study was evaluated by the incidence of vitamin D deficiency and management of hemodialysis (HD) patients with low doses of vitamin D over 6 months. This uncontrolled open-label trial was fulfilled in descriptive and then analytical phases from 2008 to 2010 recruiting chronic HD patients in our province. For this purpose, 169 patients undergoing regular HD were randomly selected and their vitamin D level was measured. Then, 54 patients with vitamin D levels less than 30 ng/mL entered the second phase. This group received 50,000 IU vitamin D3 monthly for 6 months. The mean vitamin D level in 169 patients was 21.73 ± 20.27 ng/mL. As well, 62.7% had vitamin D levels less than 30 ng/mL. Following the six-month intervention, mean vitamin D levels elevated significantly from 17.03 ± 7.4 to 42.8 ± 16.9 ng/mL (P < .0001). In this study, the incidence rate of vitamin D deficiency was 62.7%, lower than that in previous research in patients undergoing chronic HD. Vitamin D3 administration at lower doses than healthy people could significantly increase vitamin D level. Wolters Kluwer - Medknow 2023-06-30 /pmc/articles/PMC10402799/ /pubmed/37546001 http://dx.doi.org/10.4103/jehp.jehp_1507_22 Text en Copyright: © 2023 Journal of Education and Health Promotion https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Brief Report
Shahidi, Shahrzad
Mortazavi, Mojgan
Bakhtiari, Mina Bakhshali
Mirhoseini, Mohammad Sajjad
Ghasemi, Golsa
Nutritional vitamin D supplementation in chronic hemodialysis: An uncontrolled open-label trial
title Nutritional vitamin D supplementation in chronic hemodialysis: An uncontrolled open-label trial
title_full Nutritional vitamin D supplementation in chronic hemodialysis: An uncontrolled open-label trial
title_fullStr Nutritional vitamin D supplementation in chronic hemodialysis: An uncontrolled open-label trial
title_full_unstemmed Nutritional vitamin D supplementation in chronic hemodialysis: An uncontrolled open-label trial
title_short Nutritional vitamin D supplementation in chronic hemodialysis: An uncontrolled open-label trial
title_sort nutritional vitamin d supplementation in chronic hemodialysis: an uncontrolled open-label trial
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402799/
https://www.ncbi.nlm.nih.gov/pubmed/37546001
http://dx.doi.org/10.4103/jehp.jehp_1507_22
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