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A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages

OBJECTIVE: Rheumatoid Arthritis (RA) is a progressive and systemic autoimmune disorder associated with chronic and destructive joint inflammation. The hallmarks of joint synovial inflammation are cellular proliferation, extensive neoangiogenesis and infiltration of immune cells, including macrophage...

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Detalles Bibliográficos
Autores principales: Philippon, Eva M. L., van Rooijen, Lisanne J. E., Khodadust, Fatemeh, van Hamburg, Jan Piet, van der Laken, Conny J., Tas, Sander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402919/
https://www.ncbi.nlm.nih.gov/pubmed/37545512
http://dx.doi.org/10.3389/fimmu.2023.1188835