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A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages
OBJECTIVE: Rheumatoid Arthritis (RA) is a progressive and systemic autoimmune disorder associated with chronic and destructive joint inflammation. The hallmarks of joint synovial inflammation are cellular proliferation, extensive neoangiogenesis and infiltration of immune cells, including macrophage...
Autores principales: | Philippon, Eva M. L., van Rooijen, Lisanne J. E., Khodadust, Fatemeh, van Hamburg, Jan Piet, van der Laken, Conny J., Tas, Sander W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402919/ https://www.ncbi.nlm.nih.gov/pubmed/37545512 http://dx.doi.org/10.3389/fimmu.2023.1188835 |
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