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Early evaluation of waist-to-height ratio for the prediction of worsening acute pancreatitis

The purpose of this study was to evaluate the association between the waist-to-height ratio (WHtR) and the aggravation of acute pancreatitis (AP). This prospective study included AP patients treated from May 2019 to December 2019 in the Department of Gastroenterology, the First Affiliated Hospital o...

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Autores principales: Wang, Zhiyang, Xu, Yao, Yang, Kaijie, Zhou, Mengting, Huang, Deqiang, Luo, Lingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402995/
https://www.ncbi.nlm.nih.gov/pubmed/37543804
http://dx.doi.org/10.1097/MD.0000000000034515
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author Wang, Zhiyang
Xu, Yao
Yang, Kaijie
Zhou, Mengting
Huang, Deqiang
Luo, Lingyu
author_facet Wang, Zhiyang
Xu, Yao
Yang, Kaijie
Zhou, Mengting
Huang, Deqiang
Luo, Lingyu
author_sort Wang, Zhiyang
collection PubMed
description The purpose of this study was to evaluate the association between the waist-to-height ratio (WHtR) and the aggravation of acute pancreatitis (AP). This prospective study included AP patients treated from May 2019 to December 2019 in the Department of Gastroenterology, the First Affiliated Hospital of Nanchang University. Receiver operating characteristic curves were constructed to determine the optimal threshold values for predicting the aggravation of AP. Risk factor analysis was performed via logistic regression analysis. Of 258 patients included in this study, 77 (29.84%) were diagnosed with mild acute pancreatitis, 120 (46.51%) with moderately severe acute pancreatitis, and 61 (23.64%) with severe acute pancreatitis (SAP). WHtR, waist circumference, weight, and body mass index were all associated with AP severity, and the highest area under the receiver operating characteristic value was observed for WHtR. The optimal threshold WHtR value for predicting SAP was 0.567. Multivariate logistic regression analysis identified WHtR ≥ 0.567 as independent risk factor for SAP. Moreover, the hospital stay was longer and intensive care unit admission rate was higher among AP patients with a WHtR ≥ 0.567. The WHtR was found to be closely related to the severity of AP and an independent risk factor for the aggravation of AP. This simple parameter can aid the early prediction of AP progression, thereby facilitating early intervention and improving patient outcomes.
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spelling pubmed-104029952023-08-05 Early evaluation of waist-to-height ratio for the prediction of worsening acute pancreatitis Wang, Zhiyang Xu, Yao Yang, Kaijie Zhou, Mengting Huang, Deqiang Luo, Lingyu Medicine (Baltimore) 4500 The purpose of this study was to evaluate the association between the waist-to-height ratio (WHtR) and the aggravation of acute pancreatitis (AP). This prospective study included AP patients treated from May 2019 to December 2019 in the Department of Gastroenterology, the First Affiliated Hospital of Nanchang University. Receiver operating characteristic curves were constructed to determine the optimal threshold values for predicting the aggravation of AP. Risk factor analysis was performed via logistic regression analysis. Of 258 patients included in this study, 77 (29.84%) were diagnosed with mild acute pancreatitis, 120 (46.51%) with moderately severe acute pancreatitis, and 61 (23.64%) with severe acute pancreatitis (SAP). WHtR, waist circumference, weight, and body mass index were all associated with AP severity, and the highest area under the receiver operating characteristic value was observed for WHtR. The optimal threshold WHtR value for predicting SAP was 0.567. Multivariate logistic regression analysis identified WHtR ≥ 0.567 as independent risk factor for SAP. Moreover, the hospital stay was longer and intensive care unit admission rate was higher among AP patients with a WHtR ≥ 0.567. The WHtR was found to be closely related to the severity of AP and an independent risk factor for the aggravation of AP. This simple parameter can aid the early prediction of AP progression, thereby facilitating early intervention and improving patient outcomes. Lippincott Williams & Wilkins 2023-08-04 /pmc/articles/PMC10402995/ /pubmed/37543804 http://dx.doi.org/10.1097/MD.0000000000034515 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle 4500
Wang, Zhiyang
Xu, Yao
Yang, Kaijie
Zhou, Mengting
Huang, Deqiang
Luo, Lingyu
Early evaluation of waist-to-height ratio for the prediction of worsening acute pancreatitis
title Early evaluation of waist-to-height ratio for the prediction of worsening acute pancreatitis
title_full Early evaluation of waist-to-height ratio for the prediction of worsening acute pancreatitis
title_fullStr Early evaluation of waist-to-height ratio for the prediction of worsening acute pancreatitis
title_full_unstemmed Early evaluation of waist-to-height ratio for the prediction of worsening acute pancreatitis
title_short Early evaluation of waist-to-height ratio for the prediction of worsening acute pancreatitis
title_sort early evaluation of waist-to-height ratio for the prediction of worsening acute pancreatitis
topic 4500
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402995/
https://www.ncbi.nlm.nih.gov/pubmed/37543804
http://dx.doi.org/10.1097/MD.0000000000034515
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