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Electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: Retrospective study in tertiary care hospitals in Northwest Ethiopia

BACKGROUND: Myocardial infarction (MI) is diagnosed when there is a rise in cardiac biomarkers along with supportive evidence in the form of typical symptoms, suggestive electrocardiographic (ECG) changes, or imaging evidence of a new loss of viable myocardium or a new regional wall motion abnormali...

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Autores principales: Tsega, Wondale, Awoke, Worku, Sendekie, Ashenafi Kibret, Dagnew, Ephrem Mebratu, Bayih, Habtamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403055/
https://www.ncbi.nlm.nih.gov/pubmed/37540698
http://dx.doi.org/10.1371/journal.pone.0288698
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author Tsega, Wondale
Awoke, Worku
Sendekie, Ashenafi Kibret
Dagnew, Ephrem Mebratu
Bayih, Habtamu
author_facet Tsega, Wondale
Awoke, Worku
Sendekie, Ashenafi Kibret
Dagnew, Ephrem Mebratu
Bayih, Habtamu
author_sort Tsega, Wondale
collection PubMed
description BACKGROUND: Myocardial infarction (MI) is diagnosed when there is a rise in cardiac biomarkers along with supportive evidence in the form of typical symptoms, suggestive electrocardiographic (ECG) changes, or imaging evidence of a new loss of viable myocardium or a new regional wall motion abnormality. The data regarding the use of ECG and echocardiography (Echo) findings and their impact on mortality are still lacking in Ethiopia. This study assessed the utilization of ECG and Echo findings and outcomes of patients with MI in tertiary care hospitals in Northwest Ethiopia. METHODS: A retrospective chart review was conducted on patients with MI who were admitted to the adult intensive care units (ICUs) of two selected hospitals between January 2018 and July 30, 2021. Data was entered and analyzed using the SPSS 25 software. Logistic regression analysis was used to assess the association between in-hospital mortality and other variables. A P-value < 0.05 was considered significant. RESULTS: Among the 203 participants, 67.5% were male, and the mean age of the participants was 59 (13.8). Around two-thirds (66.5%) of patients had STEMI and a regional all-motion abnormality. More than half (54.1%) of the cases were in the anteroapical region. For MI, there was a 23.2% inconsistency between ECG and Echo findings. The rate of in-hospital mortality for patients with MI was 23%. Pulmonary hypertension [AOR = 7.8, 95% CI: 1.72–34.93], inferobasal regional wall motion abnormality [AOR = 7.9, 95% CI: 1.340–46.093], Killip’s classes III and IV [AOR = 2.7, 95% CI: 1.103–6.314], infection [AOR = 3.2, 95% CI: 1.108–10.65], and ischemic stroke [AOR = 1.9, 95% CI: 1.091–5.222] were significantly associated with in-hospital mortality compared with their counterparts. CONCLUSIONS: The mortality of patients with MI in this study was higher than in other reports. Killip’s class, pulmonary hypertension, infection, ischemic stroke, and inferobasal regional wall motion abnormalities were significantly associated with the in-hospital mortality of the patients with MI. There was a higher degree of inconsistency between ECG and Echo findings. The treatment of patients with MI should be tailored to their specific risk factors and causes.
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spelling pubmed-104030552023-08-05 Electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: Retrospective study in tertiary care hospitals in Northwest Ethiopia Tsega, Wondale Awoke, Worku Sendekie, Ashenafi Kibret Dagnew, Ephrem Mebratu Bayih, Habtamu PLoS One Research Article BACKGROUND: Myocardial infarction (MI) is diagnosed when there is a rise in cardiac biomarkers along with supportive evidence in the form of typical symptoms, suggestive electrocardiographic (ECG) changes, or imaging evidence of a new loss of viable myocardium or a new regional wall motion abnormality. The data regarding the use of ECG and echocardiography (Echo) findings and their impact on mortality are still lacking in Ethiopia. This study assessed the utilization of ECG and Echo findings and outcomes of patients with MI in tertiary care hospitals in Northwest Ethiopia. METHODS: A retrospective chart review was conducted on patients with MI who were admitted to the adult intensive care units (ICUs) of two selected hospitals between January 2018 and July 30, 2021. Data was entered and analyzed using the SPSS 25 software. Logistic regression analysis was used to assess the association between in-hospital mortality and other variables. A P-value < 0.05 was considered significant. RESULTS: Among the 203 participants, 67.5% were male, and the mean age of the participants was 59 (13.8). Around two-thirds (66.5%) of patients had STEMI and a regional all-motion abnormality. More than half (54.1%) of the cases were in the anteroapical region. For MI, there was a 23.2% inconsistency between ECG and Echo findings. The rate of in-hospital mortality for patients with MI was 23%. Pulmonary hypertension [AOR = 7.8, 95% CI: 1.72–34.93], inferobasal regional wall motion abnormality [AOR = 7.9, 95% CI: 1.340–46.093], Killip’s classes III and IV [AOR = 2.7, 95% CI: 1.103–6.314], infection [AOR = 3.2, 95% CI: 1.108–10.65], and ischemic stroke [AOR = 1.9, 95% CI: 1.091–5.222] were significantly associated with in-hospital mortality compared with their counterparts. CONCLUSIONS: The mortality of patients with MI in this study was higher than in other reports. Killip’s class, pulmonary hypertension, infection, ischemic stroke, and inferobasal regional wall motion abnormalities were significantly associated with the in-hospital mortality of the patients with MI. There was a higher degree of inconsistency between ECG and Echo findings. The treatment of patients with MI should be tailored to their specific risk factors and causes. Public Library of Science 2023-08-04 /pmc/articles/PMC10403055/ /pubmed/37540698 http://dx.doi.org/10.1371/journal.pone.0288698 Text en © 2023 Tsega et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Tsega, Wondale
Awoke, Worku
Sendekie, Ashenafi Kibret
Dagnew, Ephrem Mebratu
Bayih, Habtamu
Electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: Retrospective study in tertiary care hospitals in Northwest Ethiopia
title Electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: Retrospective study in tertiary care hospitals in Northwest Ethiopia
title_full Electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: Retrospective study in tertiary care hospitals in Northwest Ethiopia
title_fullStr Electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: Retrospective study in tertiary care hospitals in Northwest Ethiopia
title_full_unstemmed Electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: Retrospective study in tertiary care hospitals in Northwest Ethiopia
title_short Electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: Retrospective study in tertiary care hospitals in Northwest Ethiopia
title_sort electrocardiogram and echocardiography findings and the outcomes of patients with myocardial infarction: retrospective study in tertiary care hospitals in northwest ethiopia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403055/
https://www.ncbi.nlm.nih.gov/pubmed/37540698
http://dx.doi.org/10.1371/journal.pone.0288698
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