Selective DNA-binding of SP120 (rat ortholog of human hnRNP U) is mediated by arginine-glycine rich domain and modulated by RNA

A human protein heterogeneous ribonucleoprotein U (hnRNP U) also known as Scaffold attachment factor A (SAF-A) and its orthologous rat protein SP120 are abundant and multifunctional nuclear protein that directly binds to both DNA and RNA. The C-terminal region of hnRNP U enriched with arginine and g...

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Detalles Bibliográficos
Autores principales: Miyaji, Mary, Kawano, Shinji, Furuta, Ryohei, Murakami, Emi, Ikeda, Shogo, Tsutsui, Kimiko M., Tsutsui, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403129/
https://www.ncbi.nlm.nih.gov/pubmed/37540655
http://dx.doi.org/10.1371/journal.pone.0289599

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