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Two opposing gene expression patterns within ATRX aberrant neuroblastoma
Neuroblastoma is the most common extracranial solid tumor in children. A subgroup of high-risk patients is characterized by aberrations in the chromatin remodeller ATRX that is encoded by 35 exons. In contrast to other pediatric cancer where ATRX point mutations are most frequent, multi-exon deletio...
Autores principales: | van Gerven, Michael R., Schild, Linda, van Arkel, Jennemiek, Koopmans, Bianca, Broeils, Luuk A., Meijs, Loes A. M., van Oosterhout, Romy, van Noesel, Max M., Koster, Jan, van Hooff, Sander R., Molenaar, Jan J., van den Boogaard, Marlinde L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403137/ https://www.ncbi.nlm.nih.gov/pubmed/37540673 http://dx.doi.org/10.1371/journal.pone.0289084 |
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