A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites

Apicomplexans are widespread parasites of humans and other animals, and include the causative agents of malaria (Plasmodium species) and toxoplasmosis (Toxoplasma gondii). Existing anti-apicomplexan therapies are beset with issues around drug resistance and toxicity, and new treatment options are ne...

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Detalles Bibliográficos
Autores principales: Hayward, Jenni A., Makota, F. Victor, Cihalova, Daniela, Leonard, Rachel A., Rajendran, Esther, Zwahlen, Soraya M., Shuttleworth, Laura, Wiedemann, Ursula, Spry, Christina, Saliba, Kevin J., Maier, Alexander G., van Dooren, Giel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403144/
https://www.ncbi.nlm.nih.gov/pubmed/37471441
http://dx.doi.org/10.1371/journal.ppat.1011517

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