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Female naïve human pluripotent stem cells carry X chromosomes with Xa-like and Xi-like folding conformations

Three-dimensional (3D) genomics shows immense promise for studying X chromosome inactivation (XCI) by interrogating changes to the X chromosomes’ 3D states. Here, we sought to characterize the 3D state of the X chromosome in naïve and primed human pluripotent stem cells (hPSCs). Using chromatin trac...

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Detalles Bibliográficos
Autores principales:	Patterson, Benjamin, Yang, Bing, Tanaka, Yoshiaki, Kim, Kun-Yong, Cakir, Bilal, Xiang, Yangfei, Kim, Jonghun, Wang, Siyuan, Park, In-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403202/ https://www.ncbi.nlm.nih.gov/pubmed/37540754 http://dx.doi.org/10.1126/sciadv.adf2245

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