Cargando…

Decoding the spermatogonial stem cell niche under physiological and recovery conditions in adult mice and humans

The intricate interaction between spermatogonial stem cell (SSC) and testicular niche is essential for maintaining SSC homeostasis; however, this interaction remains largely uncharacterized. In this study, to characterize the underlying signaling pathways and related paracrine factors, we delineated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Cheng, Wang, Zhipeng, Li, Pengyu, Tang, Jielin, Jiao, Tao, Li, Yiran, Ou, Jinhuan, Zou, Dingfeng, Li, Mengzhen, Mang, Xinyu, Liu, Jun, Ma, Yanni, Wu, Xiaolong, Shi, Jie, Chen, Shitao, He, Manman, Lu, Yan, Zhang, Ning, Miao, Shiying, Sun, Fei, Wang, Linfang, Li, Kai, Yu, Jia, Song, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403211/ https://www.ncbi.nlm.nih.gov/pubmed/37540753 http://dx.doi.org/10.1126/sciadv.abq3173

Ejemplares similares

Identification of quiescent FOXC2(+) spermatogonial stem cells in adult mammals
por: Wang, Zhipeng, et al.
Publicado: (2023)

Decoding pancreatic endocrine cell differentiation and β cell regeneration in zebrafish
por: Mi, Jiarui, et al.
Publicado: (2023)

Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors
por: Grosskopf, Abigail K., et al.
Publicado: (2022)

Cellular shape reinforces niche to stem cell signaling in the small intestine
por: Pentinmikko, Nalle, et al.
Publicado: (2022)

Versatile ginsenoside Rg3 liposomes inhibit tumor metastasis by capturing circulating tumor cells and destroying metastatic niches
por: Xia, Jiaxuan, et al.
Publicado: (2022)

Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression
por: Opzoomer, James W., et al.
Publicado: (2021)

Identification of the niche and mobilization mechanism for tissue-protective multipotential bone marrow ILC progenitors
por: Liu, Qingyang, et al.
Publicado: (2022)

Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding
por: Riera-Domingo, Carla, et al.
Publicado: (2023)

Dynamic bioinspired coculture model for probing ER(+) breast cancer dormancy in the bone marrow niche
por: Pradhan, Lina, et al.
Publicado: (2023)

Single-cell profiling identifies ACE(+) granuloma macrophages as a nonpermissive niche for intracellular bacteria during persistent Salmonella infection
por: Pham, Trung H. M., et al.
Publicado: (2023)

Mechanistic insights into the enzymatic activity of E3 ligase HOIL-1L and its regulation by the linear ubiquitin chain binding
por: Xu, Xiaolong, et al.
Publicado: (2023)

Panoramic transcriptome analysis and functional screening of long noncoding RNAs in mouse spermatogenesis
por: Li, Kai, et al.
Publicado: (2021)

ATG16L1 adopts a dual–binding site mode to interact with WIPI2b in autophagy
por: Gong, Xinyu, et al.
Publicado: (2023)

Genotype-specific precision tumor therapy using mitochondrial DNA mutation-induced drug release system
por: Li, Yanan, et al.
Publicado: (2023)

Single-cell multiomics sequencing reveals the reprogramming defects in embryos generated by round spermatid injection
por: Wang, Jing, et al.
Publicado: (2022)

Oxidative stress biomarker triggered multiplexed tool for auxiliary diagnosis of atherosclerosis
por: Ma, Yuan, et al.
Publicado: (2023)

Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation
por: Wang, Fang, et al.
Publicado: (2022)

TrpA1 is a shear stress mechanosensing channel regulating intestinal stem cell proliferation in Drosophila
por: Gong, Jiaxin, et al.
Publicado: (2023)

Lipid-induced DRAM recruits STOM to lysosomes and induces LMP to promote exosome release from hepatocytes in NAFLD
por: Zhang, Jie, et al.
Publicado: (2021)

Surficial nano-deposition locoregionally yielding bactericidal super CAR-macrophages expedites periprosthetic osseointegration
por: Li, Ziyang, et al.
Publicado: (2023)

Inhalation delivery of dexamethasone with iSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and nonhuman primates
por: Meng, Qian-Fang, et al.
Publicado: (2023)

A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon
por: Tan, Lei, et al.
Publicado: (2023)

FOXG1 drives transcriptomic networks to specify principal neuron subtypes during the development of the medial pallium
por: Ba, Ru, et al.
Publicado: (2023)

The Hippo pathway mediates Semaphorin signaling
por: Meng, Zhipeng, et al.
Publicado: (2022)

Spermatogonial Stem Cell Niche and Spermatogonial Stem Cell Transplantation in Zebrafish
por: Nóbrega, Rafael Henrique, et al.
Publicado: (2010)

A wireless and battery-free wound infection sensor based on DNA hydrogel
por: Xiong, Ze, et al.
Publicado: (2021)

Mutation-induced DNMT1 cleavage drives neurodegenerative disease
por: Wang, Wencai, et al.
Publicado: (2021)

Comprehensive analysis of spatial architecture in primary liver cancer
por: Wu, Rui, et al.
Publicado: (2021)

Global lactylome reveals lactylation-dependent mechanisms underlying T(H)17 differentiation in experimental autoimmune uveitis
por: Fan, Wei, et al.
Publicado: (2023)

Charting a high-resolution roadmap for regeneration of pancreatic β cells by in vivo transdifferentiation from adult acinar cells
por: Liu, Gang, et al.
Publicado: (2023)

Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma
por: Piunti, Andrea, et al.
Publicado: (2022)

CancerVar: An artificial intelligence–empowered platform for clinical interpretation of somatic mutations in cancer
por: Li, Quan, et al.
Publicado: (2022)

Structural basis for motilin and erythromycin recognition by motilin receptor
por: You, Chongzhao, et al.
Publicado: (2023)

FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ
por: Jiang, Hua, et al.
Publicado: (2022)

CXCL12/CXCR4-Rac1–mediated migration of osteogenic precursor cells contributes to pathological new bone formation in ankylosing spondylitis
por: Cui, Haowen, et al.
Publicado: (2022)

Diversification of ranunculaceous petals in shape supports a generalized model for plant lateral organ morphogenesis and evolution
por: Cheng, Jie, et al.
Publicado: (2023)

Transformation of arginine into zero-dimensional nanomaterial endows the material with antibacterial and osteoinductive activity
por: Li, Jiaying, et al.
Publicado: (2023)

Varying mechanical forces drive sensory epithelium formation
por: Xia, Mingyu, et al.
Publicado: (2023)

An innate pathogen sensing strategy involving ubiquitination of bacterial surface proteins
por: Apte, Shruti, et al.
Publicado: (2023)

An unexpected role for Dicer as a reader of the unacetylated DNA binding domain of p53 in transcriptional regulation
por: Yang, Xin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fga96rcglqmoj1fr5rienv9jtv