Paraplegia as a Rare Clinical Presentation of Relapsed Acute Myeloid Leukemia

Myeloid sarcoma, also known as granulocytic sarcoma or chloroma, is an extra-medullary accumulation of malignant myeloid blast cells, leading to a solid tumor formation. Herein, we report a rare presentation of a case with acute myeloid leukemia (AML), whose disease relapse was clinically evident as...

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Autores principales: Osman, Haitham, Gism Elseed, Israa, Hussein, Sheikheldein B, Mando, Naima, Alraheili, Alaa A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403294/
https://www.ncbi.nlm.nih.gov/pubmed/37546146
http://dx.doi.org/10.7759/cureus.41421
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author Osman, Haitham
Gism Elseed, Israa
Hussein, Sheikheldein B
Mando, Naima
Alraheili, Alaa A
author_facet Osman, Haitham
Gism Elseed, Israa
Hussein, Sheikheldein B
Mando, Naima
Alraheili, Alaa A
author_sort Osman, Haitham
collection PubMed
description Myeloid sarcoma, also known as granulocytic sarcoma or chloroma, is an extra-medullary accumulation of malignant myeloid blast cells, leading to a solid tumor formation. Herein, we report a rare presentation of a case with acute myeloid leukemia (AML), whose disease relapse was clinically evident as acute flaccid paraplegia with a certain sensory level. On thoracic spine magnetic resonance imaging (MRI), an epidural mass compressing the spinal cord at the level of the thoracic spine segment 4 (T4) was found. The mass histology confirmed the diagnosis of myeloid sarcoma.
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spelling pubmed-104032942023-08-05 Paraplegia as a Rare Clinical Presentation of Relapsed Acute Myeloid Leukemia Osman, Haitham Gism Elseed, Israa Hussein, Sheikheldein B Mando, Naima Alraheili, Alaa A Cureus Internal Medicine Myeloid sarcoma, also known as granulocytic sarcoma or chloroma, is an extra-medullary accumulation of malignant myeloid blast cells, leading to a solid tumor formation. Herein, we report a rare presentation of a case with acute myeloid leukemia (AML), whose disease relapse was clinically evident as acute flaccid paraplegia with a certain sensory level. On thoracic spine magnetic resonance imaging (MRI), an epidural mass compressing the spinal cord at the level of the thoracic spine segment 4 (T4) was found. The mass histology confirmed the diagnosis of myeloid sarcoma. Cureus 2023-07-05 /pmc/articles/PMC10403294/ /pubmed/37546146 http://dx.doi.org/10.7759/cureus.41421 Text en Copyright © 2023, Osman et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Osman, Haitham
Gism Elseed, Israa
Hussein, Sheikheldein B
Mando, Naima
Alraheili, Alaa A
Paraplegia as a Rare Clinical Presentation of Relapsed Acute Myeloid Leukemia
title Paraplegia as a Rare Clinical Presentation of Relapsed Acute Myeloid Leukemia
title_full Paraplegia as a Rare Clinical Presentation of Relapsed Acute Myeloid Leukemia
title_fullStr Paraplegia as a Rare Clinical Presentation of Relapsed Acute Myeloid Leukemia
title_full_unstemmed Paraplegia as a Rare Clinical Presentation of Relapsed Acute Myeloid Leukemia
title_short Paraplegia as a Rare Clinical Presentation of Relapsed Acute Myeloid Leukemia
title_sort paraplegia as a rare clinical presentation of relapsed acute myeloid leukemia
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403294/
https://www.ncbi.nlm.nih.gov/pubmed/37546146
http://dx.doi.org/10.7759/cureus.41421
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AT mandonaima paraplegiaasarareclinicalpresentationofrelapsedacutemyeloidleukemia
AT alraheilialaaa paraplegiaasarareclinicalpresentationofrelapsedacutemyeloidleukemia

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