Histone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia

B-cell acute lymphoblastic leukemia (B-ALL) is an aggressive hematological disorder with a dismal prognosis. The dysregulation of histone acetylation is of great significance in the pathogenesis and progression of B-ALL. Regarded as a fundamental acetyltransferase gene, the role of HBO1 (lysine acet...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Qiu, Yingqi, Zhang, Honghao, Chang, Ning, Hu, Yuxing, Chen, Jianyu, Hu, Rong, Liao, Peiyun, Li, Zhongwei, Yang, Yulu, Cen, Qingyan, Ding, Xiangyang, Li, Meifang, Xie, Xiaoling, Li, Yuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403501/
https://www.ncbi.nlm.nih.gov/pubmed/37542030
http://dx.doi.org/10.1038/s41419-023-06019-0

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