A single-cell transcriptional landscape of immune cells shows disease-specific changes of T cell and macrophage populations in human achalasia

Achalasia is a rare motility disorder of the esophagus caused by the gradual degeneration of myenteric neurons. Immune-mediated ganglionitis has been proposed to underlie the loss of myenteric neurons. Here, we measure the immune cell transcriptional profile of paired lower esophageal sphincter (LES...

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Detalles Bibliográficos
Autores principales: Liu, Zu-Qiang, Dai, Hao, Yao, Lu, Chen, Wei-Feng, Wang, Yun, Ma, Li-Yun, Li, Xiao-Qing, Lin, Sheng-Li, He, Meng-Jiang, Gao, Ping-Ting, Liu, Xin-Yang, Xu, Jia-Xin, Xu, Xiao-Yue, Wang, Ke-Hao, Wang, Li, Chen, Luonan, Zhou, Ping-Hong, Li, Quan-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403544/
https://www.ncbi.nlm.nih.gov/pubmed/37542039
http://dx.doi.org/10.1038/s41467-023-39750-5

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