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PRC1 suppresses a female gene regulatory network to ensure testicular differentiation

Gonadal sex determination and differentiation are controlled by somatic support cells of testes (Sertoli cells) and ovaries (granulosa cells). In testes, the epigenetic mechanism that maintains chromatin states responsible for suppressing female sexual differentiation remains unclear. Here, we show...

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Detalles Bibliográficos
Autores principales: Maezawa, So, Yukawa, Masashi, Hasegawa, Kazuteru, Sugiyama, Ryo, Iizuka, Mizuho, Hu, Mengwen, Sakashita, Akihiko, Vidal, Miguel, Koseki, Haruhiko, Barski, Artem, DeFalco, Tony, Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403552/
https://www.ncbi.nlm.nih.gov/pubmed/37542070
http://dx.doi.org/10.1038/s41419-023-05996-6