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The co-delivery of adenovirus-based immune checkpoint vaccine elicits a potent anti-tumor effect in renal carcinoma

Immune-based checkpoint therapy has made significant progress in cancer treatment, but its therapeutic effect is limited. A replication-defective adenovirus (Ad) vaccine encoding tumor antigen carbonic anhydrase IX (CAIX) combined with Ad-encoding immune checkpoint PD-L1 was developed to treat renal...

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Detalles Bibliográficos
Autores principales: Jiang, Nan, Zheng, Yanyan, Ding, Jiage, Wang, Jiawei, Zhu, Fei, Wang, Meng, Sobhani, Navid, Neeli, Praveen, Wang, Gang, Li, Hailong, Zheng, Junnian, Chai, Dafei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403580/
https://www.ncbi.nlm.nih.gov/pubmed/37542081
http://dx.doi.org/10.1038/s41541-023-00706-x