SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway

Pancreatic cancer (PC), a highly lethal malignancy, commonly exhibits metabolic reprogramming that results in therapeutic vulnerabilities. Nevertheless, the mechanisms underlying the impacts of aberrant cholesterol metabolism on PC development and progression remain elusive. In this study, we found...

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Detalles Bibliográficos
Autores principales: Xu, Ruiyuan, Song, Jianlu, Ruze, Rexiati, Chen, Yuan, Yin, Xinpeng, Wang, Chengcheng, Zhao, Yupei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403582/
https://www.ncbi.nlm.nih.gov/pubmed/37542052
http://dx.doi.org/10.1038/s41419-023-05987-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403582/
https://www.ncbi.nlm.nih.gov/pubmed/37542052
http://dx.doi.org/10.1038/s41419-023-05987-7

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